Publications
15/11/2016
Optimierung der experimentellen Rahmenbedingungen zur Ermittlung des anaeroben biologischen Abbaus von Tensiden
Summary
Abschlussbericht für ein Pilot-Projekt Optimierung der experimentellen Rahmenbedingungen zur Ermittlung des anaeroben biologischen Abbaus von Tensiden. Der vorliegenden Arbeiten wurden von e...
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15/11/2016
Update of time extrapolation factors for risk assessment –the benefit of combined databases and probabilistic analyses
Introduction
In regulatory risk assessment, extrapolation factors (EFs) are used to extrapolate from experimental conditions (animal studies) to human exposure.
Time extrapolation: a short time stud...
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15/11/2016
Time extrapolation factors for risk assessment: are group specific extrapolation factors possible? (eTOXV)
Abstract
In risk assessment time extrapolationfactors (EFs) are used when a short time study is available, but chronic exposure needs to be considered.
Probabilistic analyses are needed to substanti...
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15/11/2016
Sound oral to inhalation extrapolation factors (EFs) for human health risk assessment
Introduction
• Route to Route extrapolation (R2R) is required if no in vivo data on the appropriate route are available
• R2R needs to be performed in a case by case approach for the individual...
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15/11/2016
Route to Route Extrapolation Factors for Regulatory Risk Assessment – a Probabilistic Approach
Introduction
EUROTOX 2014, 7th – 10th September 2014, Edinburgh International Conference Centre In human risk assessment any relevant exposure route (oral, inhalation and dermal) has to be addresse...
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15/11/2016
Interspecies extrapolation based on the RepDose database—A probabilistic approach
Abstract
Repeated dose toxicity studies from the RepDose database (DB) were used to determine interspecies differences for rats and mice. NOEL (no observed effect level) ratios based on systemic effe...
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15/11/2016
Evaluation of time extrapolation factors based on the database RepDose
Abstract
In chemical risk assessment for many substances only short-term animal studies are available for the evaluation of long-term human exposure. Therefore usually extrapolation factors (EF) are...
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15/11/2016
Evaluation of risk assessment factors for interspecies an dtime-extrapolation
aim
The aim of the project is to assess time and interspecies extrapolation factors based on a solid databasis using the Fraunhofer database RepDose (www.fraunhofer-repdose.de)...
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15/11/2016
Assessment factors in human health risk assessment and their associated level of safety
Abstract
Human health risk assessment of chemicals requires solid information on adverse effects after long-term exposure. Because of ethical considerations, human data or even long-term studies with...
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14/11/2016
MonitoringBase Surfactants-A Database Specifically for the Storage of Environmental Data on Surfactants in Europe
MonitoringBase Surfactants-A Database Specifically for the Storage of Environmental Data on Surfactants in Europe...
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14/11/2016
Application of ‘‘Klimisch’’ criteria to evaluate the quality of data used in surfactant monitoring studies
Abstract
CEFIC-LRI have developed a user-friendly database (MonitoringBase)(1) to store metadata and actual measurements of chemicals in the environment. A system for appraising the quality of data a...
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14/11/2016
What contribution do detergent alcohols make to sewage discharges and the marine environment?
Abstract
To investigate the potential sources for fatty alcohols arriving at a WWTP and entering the receiving waters, a study was conducted in North Wales in the catchment of the Treborth treatment...
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14/11/2016
The effect of secondary treatment and eco-region on the environmental fate of fatty alcohol based surfactants
Abstract
Samples of influent, effluent and sediments of the receiving waters of eight WWTPs were collected in each of three eco-regions of the USA, a total of 24 facilities. Six different treatment t...
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13/11/2016
Bioavailability of Cationic Surfactants [BCS] – Additional Material & Literature References
Additional Material & Literature References...
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10/11/2016
MonitoringBase Surfactants. Overview and Users’ manual Version 1.0
Introduction
Over the last 20 – 30 years, a considerable amount of resources have been spent by the detergent industries (AISE/CESIO), as well as governments and other parties, on the monitoring of...
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